20 October 2015Huracan – Defensor Sporting
Referee: Anderson Daronco (BRA, photo)
Assistant Referee 1: Emerson De Carvalho (BRA)
Assistant Referee 2: Marcelo Van Gasse (BRA)
Fourth Official: Raphael Claus (BRA)
Referee Observer: Miguel Scime (ARG)
21 October 2015
Atletico Paranaense – Sportivo Luqueno
Referee: Victor Carrillo (PER)
Assistant Referee 1: Cesar Escano (PER)
Assistant Referee 2: Jorge Yupanqui (PER)
Fourth Official: Miguel Santivañez (PER)
Referee Observer: Ednilson Corona (BRA)
River Plate – Chapecoense
Referee: Jonhatan Fuentes (URU)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Fernando Falce (URU)
Referee Observer: Carlos Coradina (ARG)
22 October 2015
Independiente – Santa Fe
Referee: Wilton Sampaio (BRA)
Assistant Referee 1: Alessandro Rocha (BRA)
Assistant Referee 2: Bruno Boschilia (BRA)
Fourth Official: Dewson Freitas (BRA)
Referee Observer: Luis Pasturenzi (ARG)