31 July – 2 August 2018El Nacional – Defensa y Justicia
Referee: Eber Aquino (PAR, photo)
Assistant Referee 1: Eduardo Cardozo (PAR)
Assistant Referee 2: Milciades Saldívar (PAR)
Fourth Official: José Méndez (PAR)
Referee Assessor: Claudio Puga (CHI)
Jorge Wilstermann – Deportivo Cuenca
Referee: Alexis Herrera (VEN)
Assistant Referee 1: Carlos López (VEN)
Assistant Referee 2: Luis Murillo (VEN)
Fourth Official: Marlon Escalante (VEN)
Referee Assessor: César Escano (PER)
Independiente Santa Fe – Rampla Jr.
Referee: Diego Haro (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Víctor Raez (PER)
Fourth Official: Luis Garay (PER)
Referee Assessor: Saúl Laverni (ARG)
Club Nacional – Botafogo
Referee: Roberto Tobar (CHI)
Assistant Referee 1: Claudio Ríos (CHI)
Assistant Referee 2: Edson Cisternas (CHI)
Fourth Official: Eduardo Gamboa (CHI)
Referee Assessor: Ricardo Casas (ARG)
Banfield – Boston River
Referee: Víctor Carrillo (PER)
Assistant Referee 1: Coty Carrera (PER)
Assistant Referee 2: Michael Orue (PER)
Fourth Official: Miguel Santiváñez (PER)
Referee Assessor: José Buitrago (COL)
Sao Paulo – Colón
Referee: Leodan González (URU)
Assistant Referee 1: Miguel Nievas (URU)
Assistant Referee 2: Carlos Barreiro (URU)
Fourth Official: Jonathan Fuentes (URU)
Referee Assessor: Carlos Torres (PAR)
Bolívar – Deportivo Cali
Referee: Ulises Mereles (PAR)
Assistant Referee 1: Juan Zorrilla (PAR)
Assistant Referee 2: Carlos Cáceres (PAR)
Fourth Official: Arnaldo Samaniego (PAR)
Referee Assessor: Juan Cardellino (URU)
Fluminense – Defensor Sporting
Referee: Germán Delfino (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Silvio Trucco (ARG)
Referee Assessor: Joel Ruiz (PAR)