First Leg, 15 October 2016Mamelodi Sundowns – Zamalek
Referee: Davies Omweno (KEN)
Assistant Referee 1: Berhe Tesfagiorghis (ERI)
Assistant Referee 2: Theogene Ndagijimana (RWA)
Second Leg, 23 October 2016
Zamalek – Mamelodi Sundowns
Referee: Bakary Gassama (GAM), photo
Assistant Referee 1: Jean Birumushahu (BDI)
Assistant Referee 2: Marwa Range (KEN)