First Leg, 20 July 2016Independiente del Valle – Atletico Nacional
Referee: Enrique Caceres (PAR, photo)
Assistant Referee 1: Eduardo Cardozo (PAR)
Assistant Referee 2: Milciades Saldivar (PAR)
Fourth Official: Ulises Mereles (PAR)
Referee Observer: Alicio Pena (BRA)
Second Leg, 27 July 2016
Atletico Nacional – Independiente del Valle
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Ariel Scime (ARG)
Fourth Official: Dario Herrera (ARG)
Referee Observer: Carlos Alarcon (PAR)